PO-01-227 CATHETER ABLATION OUTCOMES OF ATRIAL FIBRILLATION IN ELDERLY AND VERY ELDERLY PATIENTS

Age is a non-modifiable risk factor of atrial fibrillation (AF). To assess the efficacy and safety catheter ablation in Elderly Very population. All patients undergoing AF (2013-2021) with available data on follow-up were analyzed. Primary endpoint was recurrence based reported outcomes electrocardiographic documentation. Patients divided into 3 groups according to age at ablation; Non-Elderly (<65 years), (≥65 <75 years) (≥75 years). Baseline 1-year patient surveys used estimate severity score (AFSS) as well burden (mean duration frequency score; scale 0: no 10: continuous 9 frequencies/durations between). A total 7020 included (42% Non-Elderly, 42% 16%Very Elderly). Periprocedural major complications low (<1%). Pericardial effusion very uncommon but more frequent older (Non-Elderly (0.1%); 15 (0.5); 6 (0.5%); p<0.05). In all patients, direct relationship seen between increase age. However there an interaction group type. At years, after for persistent (PersAF) highest elderly (36%), followed by (30%) lowest non-Elderly (23%; lower right Figure). paroxysmal (PAF), difference while remained associated significant increased (lower left Multivariate logistic regression comparing confirmed these findings (PersAF: Elderly: HR=1.44, p<0.0001, HR=1.23, p=0.03; PAF: HR=1.29, p=0.017; HR=1.04, p=0.62) (Table). Catheter resulted improvement AFSS irrespective one year follow up (Non-Elderly:12→5., Elderly:11.5→4.5 Elderly:11.5→5; p<0.001). year, minimal (7.4 vs 1.1 1 year) (6.9 0.7) (6.5 0.6). appears be safe efficacious. have higher rate when compared or Non-Elderly. Nevertheless, significantly improved symptoms groups.Tabled 1Table - Logistic Regression Analysis Predicting Recurrence Groups:GroupHR95% CIP valueMultivariable AnalysisAll PatientsNon-Elderly years)ReferenceElderly <75)1.1461.03-1.270.009Very years)1.3811.21-1.57<0.001ParoxysmalNon-Elderly <75)1.040.89-1.210.62Very years)1.2931.04-1.590.017Non-Elderly <75)1.231.07-1.410.003Very years)1.4431.22-1.70<.0001Models adjusted sex, age, prior ablation, cardioversion, use antiarrhythmic drugs (AADs), AAD failure, Cryoballoon, posterior wall isolation. Open table new tab